Kids First Parents Association of Canada

PEER-REVIEWED RESEARCH ON CHILDREN AND COVID-19

March 27, 2020 - peer-reviewed journal comment - The Lancet: Infectious Diseases - "The many estimates of the COVID-19 case fatality rate"
  • because the total number of infected people is not known, the math cannot be done to calculate the death rate

  • estimates vary from .3% to 15%

  • the age of the people infected and the availability of medical care are factors

  • the death rate appears to be higher than seasonal 'flu and lower than SARS and MERS
March 27, 2020 - peer-reviewed research comment - The Lancet: Respiratory Medicine - "COVID-19 infection in children"
"Severe COVID-19 in children is rare....No comprehensive data are available on the impact of COVID-19 on children who are well, with an underlying condition, but it is reasonable to consider they might be at increased risk of severe disease."
March 26, 2020 - peer-reviewed research summary - Centre for Infectious Disease Research and Policy, Univ of Minnesota - "COVID-19 may spread from moms to infants and by seemingly healthy kids"
  • pregnant mothers with COVID-19 may pass it on to their newborns

  • "Kids with mild or no symptoms may spread virus"
March 26, 2020 - research letter - Journal of the American Medical Association: Pediatrics - "Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China"

March 25, 2020 - peer-reviewed research comment - The Lancet: Infectious Diseases - "COVID-19 in children: the link in the transmission chain"
"The most important finding to come from the present analysis is the clear evidence that children are susceptible to SARS-CoV-2 infection, but frequently do not have notable disease, raising the possibility that children could be facilitators of viral transmission."
March 23, 2020 - Harvard Health Publishing - summary of peer-reviewed research -"What one study from China tells us about COVID-19 and children"
"However, there is a part of the study we need to pay attention to: younger children are at higher risk of running into trouble. Among children [that tested positive] less than a year old, 10.6% had severe or critical disease. For children ages 1 to 5, that number was still high at 7.3%. It dropped to 4.2% for 6-to-10-year-olds, 4.1% for 11-to-15-year-olds, and 3% for those 16 and older. Interestingly, the only child who died was 14 years old.

It's not really surprising that the youngest children, especially infants, are more vulnerable. In most epidemics, such as influenza, it's the very young and the very old that have the highest risk."

"Although all paediatric patients in our cohort had mild or moderate type of COVID-19, the large proportion of asymptomatic children indicates the difficulty in identifying paediatric patients who do not have clear epidemiological information, leading to a dangerous situation in community-acquired infections," the authors wrote."
March 1, 2020 - peer-reviewed research - Pediatrics - "Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China"
"Children at all ages appeared susceptible to COVID-19, and there was no significant gender difference. Although clinical manifestations of children's COVID-19 cases were generally less severe than those of adults' patients, young children, particularly infants, were vulnerable to infection."



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